Meta-4 loot is so rare most mission runners won't notice its disappearance for weeks.

The problem with making meta 4 items 0.0 exclusive is that the items would then be region specific to the rat type - that runs a risk of someone ending up with a nice monopoly outcome. Removing meta 4 from high-sec, fair enough as it's that rare now it's not a big loss for most - but they shouldn't be removed from low-sec. After FW gets nerfed low-sec won't be as profitable (and anyone thinking 0.0 is more risky has never spent long around amamake etc).

The new dust tie-in might be a way for CCP to boost 0.0 income somehow (the 0.0 planets are already a nice passive income for the few who bother with the clicking). After seeing the topic about what team avatar is working on with EVA gameplay there's possibilities in that which could be used.
Then again if 0.0 space was uniformly balanced in quality and resources - what incentive is left for conflicts over resources, look at how blue lists have grown to huge sizes since systems could be upgraded, no need to go to war for better space when you can take the easy route and drop i-hubs.

Really adding more isk to the system runs a risk of inflation, it's more a need of rebalancing where the isk is generated that's needed - high-sec ores are now worth more than bistot / crokite etc. One place they could start is by looking into what basic rat items reprocess into, change it so you need to get zydrine / megacyte from low / 0.0 instead of from lvl 4 loot (make it reprocess into the same minerals as you get from mining high-sec belts).
Combine that with removing those huge spod roids from 0.0 grav belts so miners don't have to mine it out to get a respawn of decent ore would increase their income too.