Originally by: Kaaii

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Mineral prices rise and fall like a nun in a cucumber patch

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Originally by: Lord Moore

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Also, how do you overcome only being able to see in one region?

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• HOW TO RESEARCH WHAT TO TRADE
  Okay, so corporations tend to sell/buy the same thing across all their stations, mostly, so all you need to do is dock at one of the corp's stations and jot down what it sells and what it buys. The important bit in this is not to write down pricings, but to write down how many they sell/buy
• CORP FLUFF
  And the best way to find out what the station you're at BUYS, you simply go check out the corporation details listed here: background
• HOW TO FIGURE ROUTES
  So you've found station A over here that sells lots of stuff that another station B elsewhere buys lots of. what now? Make sure stations B sells something station A wants, or another station C will provide something to sell back at station A, preferably a base that will buy something from B.
the point being to make profit in both directions, otherwise you're chopping your revenue by half if you're flying empty
• HOW TO FIND BEST PROFIT
  Now you've got a list of a few corporations and the items (and how much) they sell/buy...you now look up the item information and figure out the volume of each item. You now figure out how much cargo space your industrial ship can handle - with giant cargo expanders. Put any station that sells/buys less than your cargo capacity (though some might be worth it if it's within 5%) at the bottom of your list
• EVE MARKET QUIRKS
  I just look at what the station i'm at is selling and see if there's a profit to be made hauling it to another station (and if the buy order is equal to or greater than HALF my cargo capacity)
the game seems to think that two transactions is enough to boost prices beyond profit range
And if the buy volume is less than half my cargo capacity i delete it from my list entirely.
• GIANT WHAT?!?!
  This is where investing time in escrow/market looking up best prices for named cargo expanders pays off. the critical thing is to only train industrial skill and buy named cargo expanders to get giant secure containers into your hold. Otherwise, it's a complete waste of your time and money. (training gallente indy to lvl5 is another story tho)
• THE SHORT LIST
  Finally, you've got a 'short list' of stations you can make profit on either direction. What happens now? Make custom bookmarks. Takes soooooo much time to do but it pays off, especially if you're new to the game and don't have a clue what "Iteron V with Local hull expanders plus 10mn MWD" means.
• MARKET GONE KAPUT
  Okay, so you're rolling in cash but nobody wants to sell low and buy high anymore? Go mine, or run missions or hunt 'rat spawns...or, go back to step one in a completely different part of the universe.